Platelet Rich Plasma

Platelet-rich plasma (PRP) is exactly what the name suggests. The substance is a by-product of blood (plasma) that is rich in platelets. Until now, its use has been confined to the hospital setting. This was due mainly to the cost of separating the platelets from the blood (thousands) and a large amount of blood needed (one unit) to produce a suitable quantity of platelets. New technology permits the doctor to harvest and produce a sufficient quantity of platelets from only 20-60cc of blood drawn from the patient while they are having outpatient surgery.

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Why All The Excitement About PRP?

PRP permits the body to take advantage of the normal healing pathways at a greatly accelerated rate. During the healing process, the body rushes many cells and cell types to the wound in order to initiate the healing process. One of those cell types is platelets. Platelets perform many functions, including the formation of a blood clot and the release of growth factors (GF) into the wound. These GF (platelet-derived growth factors PGDF, transforming growth factor-beta TGF, and insulin-like growth factor ILGF) function to assist the body in repairing itself by stimulating stem cells to regenerate new tissue. The more growth factors released sequestered into the wound, the more stem cells stimulated to produce new host tissue. Thus, one can easily see that PRP permits the body to heal faster and more efficiently.

A subfamily of TGF is a bone morphogenetic protein (BMP). BMP has been shown to induce the formation of new bone in research studies in animals and humans. This is of great significance to the surgeon who places dental implants. By adding PRP, and thus BMP, to the implant site with bone substitute particles, the implant surgeon can now grow bone more predictably and faster than ever before.

We can even place recombinant bone morphogenic protein (RBMP) or Infuse directly to the deficient site.

PRP Has Many Clinical Applications

Bone grafting for dental implants. This includes onlay and inlay grafts, sinus lift procedures, ridge augmentation procedures, and closure of cleft, lip, and palate defects. Repair of bone defects creating by removal of teeth or small cysts. Repair of fistulas between the sinus cavity and mouth.

PRP Also Has Many Advantages

  • Safety: PRP is a by-product of the patient’s own blood, therefore, disease transmission is not an issue.
  • Convenience: PRP can be generated in the doctor’s office while the patient is undergoing an outpatient surgical procedure, such as placement of dental implants.
  • Faster healing: The supersaturation of the wound with PRP, and thus growth factors, produces an increase of tissue synthesis and thus faster tissue regeneration.
  • Cost-effectiveness: Since PRP harvesting is done with only20-60cc of blood in the doctor’s office, the patient need not incur the expense of the harvesting procedure in hospital or at the blood bank.
  • Ease of use: PRP is easy to handle and actually improves the ease of application of bone substitute materials and bone grafting products by making them more gel-like.

Frequently Asked Questions About PRP

Is PRP safe?

Yes. During the outpatient surgical procedure, a small amount of your own blood is drawn out via the IV. This blood is then placed in the PRP centrifuge machine and spun down. In less than 15 minutes, the PRP is formed and ready to use.

Should PRP be used in all bone-grafting cases?

Not always. In some cases, there is no need for PRP. However, in the majority of cases, the application of PRP to the graft will increase the final amount of bone present in addition to making the wound heal faster and more efficiently.

Will my insurance cover the costs?

Unfortunately not. The cost of the PRP application is paid by the patient.

Can PRP be used alone to stimulate bone formation?

No. PRP must be mixed with either the patient’s own bone, a bone substitute material such as demineralized freeze-dried bone, or a synthetic bone product, such as BIO-OSS.

Are there any contraindications to PRP?

Very few. Obviously, patients with bleeding disorders or hematologic diseases do not qualify for this in-office procedure. Check with your surgeon and/or primary care physician to determine if PRP is right for you.

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Madison Avenue Oral & Maxillofacial Surgery Associates, LLC

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"I recently underwent an implant procedure with Dr. Press and his amazing team, and I cannot recommend them enough! From start to finish, my experience was exceptional. Dr. Press is an incredibly skilled oral surgeon who took the time to explain the procedure and answer all of my questions. His expertise and professionalism put me at ease, and I felt confident that I was in the best hands. The support staff was equally impressive - they were friendly, compassionate, and went above and beyond to ensure my comfort throughout the entire process. They took great care to explain post-operative instructions and were always available to address any concerns I had. Overall, my experience with Dr. Press and his team was exceptional, and I would highly recommend them to anyone in need of oral surgery. Their commitment to excellence and patient care is truly outstanding." I hope this review helps others who are considering Dr. Press and his team for their oral surgery needs.

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I had terrible jaw pain was in the office many times, and the staff and the doctor were both very compassionate. Can’t say enough about it. It was a rough time but I got through because of them. Thank you very much to everyone in your office.

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I was in mild pain for many weeks. My dentist did a full set of X-rays showings nothing. She suggested a mouthguard and thought it was TMJ even though I never had that Physical Therapy.. At some point it was getting worse. I went to a dentist/md at University hospital in Newark. He said the mouth guard was a wrong fit and type. Back to dentist. Pain became unbearable. My MD put me on oral antibiotics for 48 hours and if not better needed a ENT doctor as it might be a salivary gland problem or stone. Went to ENT..In 2 minuets, he said not salivary but teeth. He had his assistant walk me over to Dr Press' office. I had no appointment. He saw how bad my situation was and took out my wisdom tooth which an X-ray showed was over a nasty infection. He was very thorough and accommodating and pro active with my situation. He thought I might need intravenous at this point and had me back in 36 hours. At that point, the pain was unbelievable and I needed to be admitted to Morristown Medicatl Center. He called over to the on call oral surgeon and got me on intravenous meds quickly. I was in the hospital 6 days. Dr Press came and put an outside drain in and then took it out 4 days later. I have been followed by his office and just discharged. I cannot say enough good things about Dr. Press. He has an impeccable reputation and I can see why.

- Marlene G

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Going into my appt. for a wisdom tooth extraction, I was highly anxious. From the moment I met the first medical team member, my fears were tamped down and everyone treated me with warmth and kindness and answered all of my questions honestly and with concern. Dr. Press reviewed the entire procedure and the post-procedure expectations clearly. The procedure itself was so quick and so painless (truth!); I am so appreciative of everyone who took care of me from arrival through check out.

- Kara M

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If your looking for an oral surgeon, I highly recommend Dr. Kenneth Press. Everyone is afraid of a dentist, but his staff and the Doctor immediately makes you feel comfortable and relaxed. I had a tooth pulled expecting some discomfort which never happened. Amazing to say, Not one discomfort or side effect. I walked out with no pain, and back to work the same day! Looking forward to another tooth pulled πŸ™‚

- Jackie S

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Everyone in the office is so kind and caring. Dr Press is very professional and an excellent surgeon.

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Overall, a great experience!

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